Forums » Oncology

Prednisone (as sole agent) dose for neoplasia

    • 44 posts
    January 10, 2014 5:51 PM EST

    When clients refuse further diagnostics/care and all I can do for that presumptive neoplasia case is prednisone.... how much should I be giving?

    0.5 mg/kg? 1 mg/kg? 2 mg/kg?

    Should I be dosing by body surface area instead (or does it not really matter for pred?)


    And would you use a higher dose for cats than dogs?



    • 26 posts
    January 13, 2014 5:06 PM EST


    I would use an anti-inflammatory dose that you are comforatable. I typically use 30 mg/m2 as my high dose, but there is no magic in that number.

    My typical cat dose is 5 mg BID unless the cat is below 5 kg, in which case I use 5 mg once daily--and I always use prednisolone in cats.


    • 44 posts
    February 7, 2014 12:40 PM EST

    Do you prefer once daily dosing or twice daily dosing, or does it not really matter?


    30 mg/m2 is approximately 1 mg/kg (correct me if I'm wrong). Would you prefer 1 mg/kg q24h in a lymphoma dog, or instead 0.5 mg/kg q12h?

    • 26 posts
    April 13, 2014 11:43 AM EDT


    For me, whether we use once or twice daily depends more on client preference, than on anything else. Both dosing regimens should work.