Continuing Education  » Neurology  » What’s Feeding Those Seizures? An Update On Refractory Canine Epilepsy And The Poten...

What’s Feeding Those Seizures? An Update On Refractory Canine Epilepsy And The Potential Link to Gastrointestinal Health

CE Event Information

  • Description:
    Approximately one-third of dogs with idiopathic epilepsy fail to achieve satisfactory seizure control with antiepileptic medication, and are considered to have refractory epilepsy.  These dogs are at greater risk of disease-related complications and death associated with their uncontrolled seizures.  

    The mechanisms that lead to refractory epilepsy remain poorly understood.  However, there is increasing evidence to suggest that an important interaction exists between the gastrointestinal tract and the brain - the so called microbiota-gut-brain axis – that is vital for maintaining homeostasis of the nervous system and can influence susceptibility to disease.

    This presentation includes discussion of refractory epilepsy in dogs, with a review of its clinical characteristics and our current understanding of the mechanisms that can result in drug resistant seizures. The concept of the microbiota-gut-brain axis is also be introduced, and evidence presented to demonstrate the role that the gastrointestinal system plays in the development and progression of epilepsy and other neurological disorders in humans.  Finally, published information on the link between the gastrointestinal tract and epilepsy in dogs is reviewed, and future directions for research explored.

    Running time: 1 hour

    CE credit eligible for Premium Membership subscribers only or as a pay-per-view ($28). To view at no charge / non-CE credit visit:

  • Sponsor: AKC Canine Health Foundation
  • Presenter(s): Karen R. Muñana, DVM, MS, DACVIM (Neurology)
  • Fee (Basic Membership): $28

Featured Publications

The following journal articles or textbook chapters have been selected as Supplements to this event. You can elect to purchase them as part of a discounted seminar package fee.
Prepaid CE Subscribers will be assessed a supplement fee for articles purchased.

  • Seizures and Status Epilepticus

    Small Animal Critical Care Medicine (Second Edition), 2015, Chapter 82, Pages 426-431. Author: Karen M. Vernau Member fee: $5.95 - Login to ...  more
  • Anticonvulsants

    Small Animal Critical Care Medicine (Second Edition), 2015, Chapter 166, Pages 872-876. Authors: Adam Moeser, Sheldon A. Steinberg Member fe...  more
  • Phenobarbital or potassium bromide as an add-on antiepileptic drug for the management of canine idiopathic epilepsy refractory to imepitoin

    The Veterinary Journal, 220 (2017), pp 51-54. Authors: E Royaux, L Van Ham, BJG Broeckx, I Van Soens, et al. Login to Purchase Member fee: $7.95