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Evaluation of Erythrocytes

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Description:
Veterinary Hematology, 2012, Chapter 4, Pages 49-121. Author: John W. Harvey

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Chapter Outline

Normal Erythrocytes

Erythrocyte Morphology
Erythrocyte Functions
Erythrocyte Biochemistry
Membrane Structure and Function
ATP Generation
2,3DPG Pathway
Oxidant Injury
Methemoglobin Formation and Reduction
Iron Metabolism
Erythrocyte Destruction
Normal Removal of Aged Erythrocytes
Pathologic Destruction of Erythrocytes
Abnormal Erythrocyte Morphology
Rouleaux
Agglutination
Polychromasia
Anisocytosis
Hypochromasia
Poikilocytosis
Echinocytes (Crenated Erythrocytes)
Acanthocytes
Keratocytes
Stomatocytes
Spherocytes
Schistocytes
Leptocytes
Eccentrocytes
Pyknocytes
Elliptocytes (Ovalocytes)
Dacryocytes
Drepanocytes (Sickle Cells)
Crystallized Hemoglobin
Lysed Erythrocytes
Erythroid Loops
Erythrocyte Vesicles
Nucleated Erythrocytes
Inclusions of Erythrocytes
Howell-Jolly Bodies (Micronuclei)
Heinz Bodies
Basophilic Stippling
Siderotic Inclusions
Cabot Rings
Infectious Agents of Erythrocytes
Babesia Species
Theileria Species
Cytauxzoon felis
Anaplasma Species
Distemper Inclusions
Hemotropic Mycoplasmas (Hemoplasmas)
Bartonella Species
Artifacts Resembling Infectious Agents
Erythrocyte Assays
Erythrocyte Counts, Hematocrit, and Hemoglobin Content
Reticulocyte Counts
Erythrocyte Indices
Mean Cell Volume
Mean Cell Hemoglobin Concentration
Mean Cell Hemoglobin
Red Cell Distribution Width
Erythrocyte Volume Histograms and Erythrocyte Cytograms
Direct Antiglobulin Test
Methemoglobin Determination
Toxic Methemoglobinemia
Cytochrome-b₅ Reductase Deficiency
Serum Iron Assays
Serum Iron
Total Iron-Binding Capacity
Serum Ferritin
Erythropoietin Assay
Differential Diagnosis of Anemia
Regenerative Versus Nonregenerative Anemia
Classification of Anemia Using Erythrocyte Indices
Hemolytic Anemias
Immune-Mediated Hemolytic Anemia
Primary IMHA
Neonatal Isoerythrolysis
Transfusion Reactions
Erythrocyte Parasites
Babesia Species
Theileria Species
Cytauxzoon felis
Anaplasma Species
Hemotropic Mycoplasmas (Hemoplasmas)
Other Infectious Agents
Chemicals and Plants
Oxidants
Venoms
Drugs Causing Immune-Mediated Anemia
Fragmentation
Hypo-osmolality
Hypophosphatemia
Hereditary Erythrocyte Defects
Pyruvate Kinase Deficiency in Dogs and Cats
Phosphofructokinase Deficiency in Dogs
Increased Erythrocyte Osmotic Fragility in Cats
Hereditary Spherocytosis in Cattle
Glucose-6-Phosphate Dehydrogenase Deficiency in a Horse
Erythrocyte Flavin Adenine Dinucleotide Deficiency in Horses
Hereditary Stomatocytosis in Dogs
Additional Hereditary Defects
Miscellaneous Causes of Hemolytic Anemia
Splenic Disorders
Liver Failure in Horses
Postparturient Hemoglobinuria in Dairy Cattle
Blood-Loss Anemias
Anemias Resulting from Decreased Erythrocyte Production
Nonregenerative Anemias without Leukopenia or Thrombocytopenia
Hormone Deficiencies
Anemia of Inflammatory Disease (Anemia of Chronic Disease)
Disorders of Nucleic Acid Synthesis
Abnormalities in Heme Synthesis
Nonregenerative Immune-Mediated Anemia
Selective Erythroid Aplasia
Dyserythropoiesis
Nonregenerative Anemias with Leukopenia and/or Thrombocytopenia
Hypocellular/Aplastic Bone Marrow
Myelophthisic Disorders
Physiologic Anemia of Neonatal Animals
Erythrocytosis (Polycythemia)
Relative Erythrocytosis
Absolute Erythrocytosis
Differential Diagnosis of Erythrocytosis
References

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