Upcoming CE

• 
  

  Canine Degenerative Myelopathy: From Gene Mutation Discovery to Clinical Trials

  • Date: October 17, 2019
  • Presented by: Joan R. Coates, DVM, MS, Diplomate ACVIM (Neurology)
  • Sponsored by: AKC Canine Health Foundation
  • Degenerative myelopathy (DM) is an inherited, adult-onset disease of the spinal cord causing progressive weakness and paralysis of the hind limbs and eventually all limbs. DM has clinical, histopathologic, and genetic parallels to amyotrophic lateral scle...  moreDegenerative myelopathy (DM) is an inherited, adult-onset disease of the spinal cord causing progressive weakness and paralysis of the hind limbs and eventually all limbs. DM has clinical, histopathologic, and genetic parallels to amyotrophic lateral sclerosis (ALS - Lou Gehrig's disease) in humans. Mutations in an enzyme that converts superoxide to water and hydrogen peroxide, superoxide dismutase 1 (SOD1), have been linked to DM and human ALS. These discoveries have guided studies to further understand natural history, establish biomarkers, and initiate clinical trials for therapeutic strategies. Join us in this webinar for a better understanding of DM including: - Genetic testing results as a risk factor for canine degenerative myelopathy - The neurologic progression in affected patients in terms of disease spread and changes in neuroanatomic localization - The pathophysiology of the mutated SOD1 protein and its consequences in the multifactorial pathogenesis of canine degenerative myelopathy - A platform of ...    less
  Canine Degenerative Myelopathy: From Gen..
• 
  

  Addressing the Spay / Neuter Conundrum in Dogs: Some Breed-specific and Body Size-specific Guidelines

  • Date: November 20, 2019
  • Presented by: Ben Hart, DVM, PhD, DACVB
  • Sponsored by: AKC Canine Health Foundation
  • The practice of early spay/neuter for companion dogs not intended for breeding has been standard for decades. The proposed reasons are several, including preventing unwanted pregnancies, preventing unwanted aggression, and preventing mammary cancer (none ...  moreThe practice of early spay/neuter for companion dogs not intended for breeding has been standard for decades. The proposed reasons are several, including preventing unwanted pregnancies, preventing unwanted aggression, and preventing mammary cancer (none of which has evidence-based support). In contrast, over the past decade, several investigators have reported an increase in certain cancers and joint disorders that have increased in association with spay or neuter. However, these findings were not clinically useful because breeds were generally lumped together, as were ages of spay/neuter. UC Davis recently completed collection of data from extensive veterinary hospital records on 35 dog breeds and 5 weight categories of mixed breed dogs, showing major differences in vulnerability to the effects of gonadectomy on the prevalence of joint disorders and cancers. For example, with some specific breeds there is no impact of spay/neuter at any age or the occurrence of joint disorders or cancers, while there are certa...    less
  Addressing the Spay / Neuter Conundrum i..
• More CE events