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VetVine Client Care
Typical And Atypical Addison's Disease
Internal Medicine
This question was asked in regard to a past webinar on the topic of Canine Addison's Disease:
Question:
Why do only some dogs with atypical Addison's disease convert to typical Addison's disease?
Answer by Elisabeth Zenger, DVM, PhD, DACVIM (SAIM):
Actually most dogs with "atyical" (a term that is recommended to not be used) Addison's do eventually need mineralocorticoid supplementation. When aldosterone is measured, the vast majority of "atypical" Addisonian's are found to be deficient in aldosterone. There are likely compensatory mechanisms in play that keep these dogs from having the typical electrolytes changes. In the rare case where aldosterone is normal, secondary Addison's disease should be investigated.